Tramadol: The Need, The Abuse, The Effect and The Solution.

Tramadol,sold under the brandnameUltramamong others, is an opioid pain medication used to treat moderate to moderately severe pain. When taken as an immediate-release oral formulation, the onset of pain relief usually occurs within about an hour. It has two different mechanisms. First, it binds to the μ-opioid receptor. Second, it inhibits the reuptake of serotonin and norepinephrine.
Tramadol is marketed as a racemic mixture of bothR- andS-stereoisomers. This is because the two isomers complement each other's analgesic activity. It is often combined with paracetamol (acetaminophen) as this is known to improve the efficacy of tramadol in relieving pain.
Tramadol is metabolized toO-desmethyltramadol, which is a more potent opioid. It is of the benzenoid class.
Tramadol was launched and marketed as "Tramal" by the German pharmaceutical company Grünenthal GmbH in 1977 in West Germany, and 20 years later it was launched in countries such as the UK, US, and Australia. It is marketed under many brand names worldwide.
The Need
Tramadol is used primarily to treat mild–severe pain, both acute and chronic.
Its analgesic effects take about one hour to come into effect and 2–4 hours to peak after oral administration with an immediate-release formulation. On a dose-by-dose basis tramadol has about one-tenth the potency of morphine and is approximately equally potent when compared to pethidine and codeine.
The Abuse
Tramadol is also commonly abused with other substances and is frequently mixed with alcohol. However, opioids like tramadol actually increase the effects of alcohol.
In general, tramadol is taken orally. If you take tramadol more often, in higher doses, or in ways other than prescribed…you are abusing tramadol.
Can tramadol be abused?
Yes. Tramadol can be abused!
While many doctors consider tramadol to be a relatively safe opioid and prescribe it because of its low potential for abuse, abuse still occurs. Any alteration to the prescription directions (such as taking more tramadol, more often than prescribed) can lead to problems. In fact, when you abuse tramadol (eg. when you snort tramadol), you are at risk of adverse side effects of the medication and possibly addiction.Misuse of opioids like tramadol is a one of the tramadol addiction signs.
How tramadol is abused
You abuse tramadol when you change the way you are supposed to take tramadol. In general, tramadol is taken orally. Ways of taking tramadolthat define tramadol abuse include:
*.chewing tramadol
*.injecting tramadol
*.smoking tramadol
*.snorting tramadol
*.taking tramadol in higher doses than prescribed
*.taking tramadol more often than prescribed
*.using tramadol with alcohol or other drugs. Source of this news: Click Banner below : To View picture in this News and more Click the Banner below :
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